Scientists Explore Ways to Lure Viruses to Their Death

Some scientists are exploring a fundamentally different strategy to fight viruses. They want to wipe them out by luring them to their destruction, like mice to mousetraps.

There are only a few basic ways to fight viruses. A vaccine can prime the immune system to attack them as soon as they invade the body. If a virus manages to establish itself, a doctor may be able to prescribe a drug to slow down its spread. And if all else fails, a doctor may quarantine a patient to head off an epidemic.

Viruses invade a cell by latching onto certain proteins on its surface. Once attached, they can slip inside the cell and manipulate it into making new copies of themselves. But viruses cannot infect red blood cells. Unlike most other cells in the body, as red blood cells develop in bone marrow they lose their DNA. If a virus ends up inside a red blood cell, there are no genes it can hijack to replicate itself.

“It occurred to us that if a virus bound to a red blood cell, that was a dead end,” said Dr. Robert W. Finberg, a professor at the University of Massachusetts Medical School.

Read full story in The New York Times.